It might also boost levels of naturally occurring endocannabinoids, which may explain its seemingly broad range of uses. More recently, scientists have discovered that certain components of marijuana, including CBD, are responsible for its pain-relieving effects. They reported feeling less anxiety and discomfort.
Sativex also relieved pain in another study of people with multiple sclerosis. Another study examined the effects of CBD on human sebocytes, the skin cells that produce sebum, the oily substance that plays the central role in acne. Many animal studies on the effects of CBD on mood disorders showed promising results. Interestingly, the single dose of CBD led the men to experience a smaller blood pressure increase than normal in response to these tests (34). CBD does not have any addictive properties, doesn’t cause withdrawal, and there’s no evidence that it produces tolerance when used regularly for long periods of time. So far, early research has shown that CBD and other cannabinoid based therapies have the potential to help with everything from anxiety to difficult-to-treat conditions or symptoms such as chronic pain. Better known as CBD, it is one of over 100 chemical compounds known as cannabinoids found in the cannabis or marijuana plant, Cannabis sativa (1). One study of 94 cannabis users found that those who smoked high-CBD strains of marijuana scored better on ratings of cannabis addiction. Researchers suggest that CBD may help relieve anxiety associated with the anticipation of a fearful event. Patients who use medical cannabis have also found it helpful in pain related to autoimmune arthritis and similar disorders, normally high CBD varieties. Specialists warn about risks of cannabis edibles.
A similar study found that CBD counteracted the development of memory problems in rats with Alzeihmers disease (AD). Side effects noted in studies include (40): CBD is also known to interact with several medications. It might be tempting to smoke all those stems that are gathering dust in your jar, but you may want to think twice before lighting up. For one, CBD can lower elevated blood pressure, one of the key risk factors for stroke and other cardiovascular diseases. A human study published in the Journal of Clinical Investigationfound that the oil prevented activity in sebaceous glands. A study published in the American Journal of Psychiatry explored CBD’s effect on cue-inducing craving and anxiety in people with heroin use disorder. This spray that contained both THC and CBD may also have anti-inflammatory properties. This is especially important if you take medications or supplements that come with a “grapefruit warning.” Both grapefruit and CBD interfere with cytochromes P450 (CYPs), a group of enzymes that are important to drug metabolism (42).
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